Sunday, February 20, 2011

Grief, Pain, Freud, and Melzack (Don't worry... this post is way more fun than it sounds)

I’m currently doing a masters thesis on the topic of pain. It’s interesting (to me). I’m examining the multiple determinants of pain in a sample of cardiac patients. So I’m studying the relationships among psychological and biological factors in predicting angina, a particular type of pain brought on by CAD. The reason I got interested in this area is that the heart has for so long been considered an organ tightly related to emotions (see this awesome website http://www.heartsymbol.com/) and because I have had chest pain since I was a child (Research is Me-search…)

The most interesting thing I have found about the topic of pain (read: emotional distress) is the combination of 2 theories: 1) the Neuromatrix Theory of pain (Melzack, 1993, 1999), and 2) Freud’s psychosexual theory of development.

Yes.

Here’s how.

Freud, as we know, was a neurologist (Galbis-Reig, 2004).  His theory, which many these days shorten to “aggression and sex”, was actually intended to indicate that the neural loops (he didn't use those words) laid down as children would dramatically influence personality later in life. He took his theory further in the discussion of “trauma”: the traumas of childhood were repeated in experiences in adulthood. (He was not the first to have this thought: http://en.wikipedia.org/wiki/Eternal_return#Friedrich_Nietzsche.)

But let's translate this into psychological distress speak: The emotional distress established in childhood would be repeated in adulthood.

Crazy talk? Maybe. (Of course not.) But then let’s fast-forward 100 years (give or take.) and get to Melzack’s new and improved theory of pain.  This theory is designed to explain physical pain, and grew out of observations of phantom limb pain, where in fact a limb that has been amputated seems to cause intense physical pain.

Melzack’s theory is a complicated piece of psychological thought, but boils down to this: 1) we have the capacity to feel pain, 2) this capacity is both innate (i.e., we are genetically predisposed to knowing what ‘burn’, ‘itch’, ‘peirce’ feels like) and learned (i.e., if we have been burned before, now we REALLY know what that feels like). According to this theory, there is no need for the peripheral body’s existence in order for humans to feel pain because the experience of pain only becomes translated in neural loops that ‘code for’ certain types of pain. That is to say that if you didn’t have a body, and were nothing but your brain, I could make you feel any type of bodily pain just by activating the right neurons. (I wouldn’t though.)

Doesn’t this sound to you a lot like the physiological version of Freud’s trauma theory? Especially when you think of chronic pains like back pain, joint pain, and oh recurrent chest pain. Some pattern for these pains gets laid down early on in life, and 20 years later, people are still complaining about it because it got worse. (And just in case you were wondering, there is a terribly poor relationship between how bad it hurts and how bad it's broken. That means, it doesn't always hurt more because it's more broken. Sometimes it is, sometimes it isn't.)

So what about a psychological neuromatrix? Old pains, laid down in childhood (rejection, abandonment, grief), would have formed their own neural loops, and the more those pains were felt, experienced, reminded, … the more practiced the neural loops became. The more practiced those loops become, the easier it is to activate them, until they would come to dominate. Until you couldn’t feel anything else. That's why childhood trauma is so bad. The neural loops for happy would be rusty, the neural loop for love may have atrophied…You need to practice those too, you know.

As an aside. Have you ever noticed how some people refuse to feel bad? (Those people annoy me.) You have a bad day and they say something along the lines of 'it'll be better tomorrow', as if anybody cares. But maybe those people are on to something. Maybe it's related to this fear of losing the ability to feel good if you spend too much time feeling bad that prompts some people to say “don’t be sad” when you’re sad. (Or just be sad for three days. THREE DAYS? See Paulo Coelho’s blog http://paulocoelhoblog.com/2011/02/18/past-and-present/ Some religions suggest to keep mourning down to a minimum too… I’m thinking Islam and Hinduism and I think there are others too http://en.wikipedia.org/wiki/Mourning). And maybe there's sound scientific logic behind this. Maybe we want to make sure we keep the neural loops for pain unpracticed. I think there’s something to that. You always need to remember that it is possible to feel good, and you should practice feeling good so that your mind (and brain) gets used to it.  

BUT – here’s the twist. Ignoring negative emotions doesn’t work. Psychology is all about not allowing people to repress negative emotion. Therapy is all about feeling those emotions, and realizing that that’s the only way through them. That was Freud's big discovery. (And yes I know that therapy has a bad track record when it comes to oh working and all... But more on that later. I'm still on this whole feeling-the-burn kick.)

As long as I'm bringing religion into this, “turn the other cheek” is a Biblical quote often used to encourage forgiveness over revenge. But I think it makes more sense to think of “turning the other cheek” as a response to something or someone causing you pain. For example, if someone hurts you, let’s say through rejection, and you get mad. Then the whole concept of an eye for an eye kind of breaks down doesn’t it? What are you going to take revenge on? And I think this happens a lot in romantic relationships: someone screws you over, and you go screw somebody else over to feel better about things (because often it’s impossible to take revenge off the original person). Does it work? Uhh. Don’t think so. (An other interesting site : http://www.healmybrokenheart.com/)
 
But turn the other cheek? That makes sense. It says “fine, go ahead and hurt me, hurt me again because I am going to deal with these emotions”. You know what that sounds like? Systematic desensitization (Wolpe, 1961)! The process of exposure through which people are taught to get over all sorts of things from snake phobias to motor vehicle accidents. Exposure seems to be the best form of therapy for dealing with trauma or post-traumatic stress disorder. In my opinion (and I’m sure I could find some references to back me up), the main ingredient operating in ANY form of therapy is exposure: therapists encourage patients to try new things, to form new relationships, to expose themselves to their fears – and then offer them the support they need to talk about those experiences, to experience them, to see how they are similar and different from the previous experiences that left a hurtful and sensitive neural trace.

The process of therapy is probably related to the process of creating new neural loops that are not painful, but that contain some elements from the painful neural loops. Some ingredients that seem to make therapy particularly useful (and likely to work...) are reflection and validation. These are fun ways that let the person know you connect with them, and your best friend is probably pretty good at this (though your parents may not have been...) 

But yes, reflection and validation... Possibly the way around the whole painful neural loops thing. how? I don't know, I'm just speculating here and this post is getting way too long. But it wouldn't surprise me if this activated mirror neurons that were instrumental in the process of building new neural loops... Hmmm. More to come.

4 comments:

  1. Damned cool post! (Love your style, Nad.)

    The neural loops thing is so compelling. Sounds like we can teach ourselves to experience pain as even more painful.

    Is there a role for using pain to get what you want (A power grab, ala Nietzsche)? Like, I get to be the center of attention when I hurt, so MAN, is my fibromyalgia acting up again today or WHAT?

    I'm a bit confused though. Sounds like at the end, turning the other cheek/exposure desensitization would similarly teach pain.... How does re-running the loop here differ from Melzack's learning of pain?

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  2. Omg I'm so happy you asked!!! =)

    I will have to give this issue more thought but here is what I'm thinking: Re-running the loop 'on automatic' may be different from re-running the loop with awareness.

    In psychojargon-speak, it would be the difference between 'processing' your pain (i.e., feeling it and accepting it, which somehow enables you to eventually let it go), and just being a victim of it and engaging in more or less efficient coping behavior (e.g., alcohol or other addictions) to just make it go away - which often just makes things worse.

    It`s complicated though - and there's the moderating force of social support involved in this too... (We'll get to that!)

    As to your other point: Yes! Secondary gain is HUGE in pain perception and reporting. There is even some suggestion that people with people around to listen to them are going to be MORE likely to complain about symptoms and pain than people with nobody around to listen to them. (If you're thinking that seems to go against the usual notion of social support as PROTECTIVE against medical/psychological complaints, I am too.)

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  3. WOW - Nadine, this post is SO COOL!!!!

    Seriously, this was mega-interesting and the comparisons you drew between Melzack and Freud as two sides of the pain coin were very well written!

    AND as soon as I was thinking "But what about sensitization?" in my head, BAM! There it was, in your post!

    See, I've always thought the reflection and validation part of the therapeutic process was more about "Reframing" your negative events, and through a reactivation of those patterns, slowly teaching your brain (and heart and soul!) new reactions - rewiring the whole system, as it were. Hence CBT - replacing your old, harmful thoughts with new, supportive ones. And even if you don't believe them at first, training your brain to THINK them means that next time you'll be more likely to naturally take that path instead of the scary one.

    I mean, that's exactly how memory reconsolidation works. Nader's work with PTSD mice (I know, I know, I only know his research cuz that's where I did my project! I miss neuroscience so bad sometimes...) did exactly that - he'd have them develop a trauma to their shock-cages (contextual fear conditioning) the put the mice BACK there so that they were suitably terrified based on what happened before. Now here's the cool part - the "memory" of the cage, when re-activated, is in a labile state again. Meaning it can be manipulated. So he'd inject his drug (a protein synthesis inhibitor, if I remember right) and then take the mice away.
    The NEXT day when they went back in the cage - guess what? They weren't scared! Because the drug prevented the memory from being Re-consolidated, it dissipated (or at least diminished) how FREAKIN COOL IS THAT!?!

    So I'd think it's the same with chronic angina or emotional turmoil. I mean, you never see a child who was SO emotionally abused that he's immune to it in life, right? Of course not! You see really messed up kids who naturally fall into the same patterns that have been reconsolidated their whole lives.

    So maybe that's why "ignoring" negative emotions is so frowned upon. Because without dealing with the emotion you're just bringing up the same neural loops and if you don't fix it they're getting stronger than ever!


    ...okay, I rambled there. But basically - I totally loved this post!!!!

    Also, you've always had chest pain? Really?

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  4. About the chest pain, yes, actually. (It's no bueno.)

    I totally love your point about memory reconsolidation! It's exactly what Nader says!

    You need to 1) re-activate the neural loop, and 2) intervene while it is in this labile state where you can CHANGE it.

    Thank you for commenting :) I love how you bring this perspective!

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